Lupus tumidus is considered a rare subtype of chronic cutaneous lupus erythematosus, characterized by erythema and bright urticarial erythematous- violaceous. Tumid lupus erythematosus (TLE), also known as lupus erythematosus tumidus, is a highly photosensitive form of cutaneous lupus erythematosus (cutaneous. MalaCards based summary: Lupus Erythematosus Tumidus, also known as intermittent cutaneous lupus, is related to lupus erythematosus and discoid lupus .

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Despite the histopathologic similarities to lupus tumidus, the lymphocytic infiltration is usually less dense and mucin accumulates mainly at the papillary dermis in REM.

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There was no significant difference in outcome between the two different antimalarial treatments. Once a lesion has developed, it can disappear spontaneously within a few days or weeks, even if the disease recurs chronically in patients with LET. Chronic cutaneous lupus erythematosus. None of the 40 patients had a history of drug-induced LET in our study after up to 15 years of follow-up. The clinical distinction between PLE and LET can be difficult; however, LET shows a much more delayed reaction after sun exposure, and healing of skin lesions luppus much longer, even when sun exposure is avoided and a sun block is applied daily.


It is important to distinguish LET from other variants of CLE based on histology and clinical features since the course of disease and treatment response significantly differs. Other distinguishing histologic features of the major clinical variants of lupus erythematosus involving the skin are noted in Table 1.

Lupus Erythematosus Tumidus: A Unique Disease Entity

Indian Dermatology Online Journal. Abstract Lupus erythematosus tumidus LET is a photosensitive skin disease characterized by succulent, edematous, and non-scarring plaques. Views Read Edit View history. The clinical picture, one of the major criteria of LET, is characterized by nonscarring, erythematous, succulent, urticarialike single or multiple plaques with no surface changes such as follicular plugging Figure 1.

Med Clin North Am.

Tumid lupus erythematosus Tumid lupus erythematosus also known as “lupus erythematosus tumidus” [1] is a rare, but distinctive entity in which patients present with edematous erythematous plaques, usually on the trunk. Many are sick, young, fair-skinned females. As previously described, 15 results of direct immunfluorescence staining of lesional skin specimens of LET have mostly lpuus negative for immunoglobulin or lupue components.

Due to the rarity of cases reported, we emphasize the importance of detailed clinical examination supplemented by histopathological study since isolated examination may lead to underdiagnosing the disease.

Tumid lupus erythematosus – Wikipedia

She also mentioned the appearance of a small erythematous-infiltrated plaque about two centimeters in diameter at the left frontoparietal region fifteen days before the medical appointment. This cutaneous condition article is a stub. Lupus erythematosus tumidus—a neglected subset of cutaneous Lupus erythematosus: Further systemic manifestations, such as renal, central nervous system, or lung involvement, have not yet manifested in any oupus the 40 patients during our study after up to 15 years.


Features of neonatal cutaneous LE may include:. Young women are most often affected, and there is no restriction to race or age.

Active and burned-out disease can lead to social isolation and depression. Lupus erythematosus is lpus multisystem, heterogeneous, autoimmune disease characterized by the production of autoantibodies against cellular constituents. Important predisposing factors for cutaneous LE include:.

Discussion LET is a photosensitive skin disease that is characterized by succulent, edematous, non-scarring plaques.

Cutaneous lupus erythematosus | DermNet NZ

Nearly all the case reports of LET in the literature are published by European countries, especially Germany and France, indicating that many more white patients are seen. Support Center Support Center. Create a personal account to register for email alerts with links to free full-text articles. The same group reported interstitial mucin deposition as a further characteristic feature of LET and results of direct immunofluorescence staining as often being negative; however, there was no doubt about LET being a separate subset of CCLE.

Histologic features include perivascular and periadnexal lymphocytic infiltration and interstitial mucin deposition. Intermittent cutaneous lupus erythematosus.