We describe two cases of erythema induratum of Bazin (EIB), a cutaneous form of TB. •. Cases had no signs of active TB, but had a positive Interferon Gamma. Erythema induratum is a panniculitis on the calves. It occurs mainly in women, but it is very rare defined pathogen. The medical eponym Bazin disease was historically synonymous, but it applies only to the tuberculous form and is dated. Erythema induratum (also referred to as erythema induratum of Bazin (EIB) or nodular vasculitis) is a chronic nodular skin disease that is thought to represent a .
|Published (Last):||19 October 2006|
|PDF File Size:||2.90 Mb|
|ePub File Size:||6.1 Mb|
|Price:||Free* [*Free Regsitration Required]|
In patients with moderate to severe symptoms, encourage the use of combination medical and physical modalities for potential synergistic effects. This section is empty. From Wikipedia, the free encyclopedia.
Disorders of subcutaneous fat M Historically, when it has occurred, it has often been concomitant with cutaneous tuberculosisand it was formerly thought to be always a reaction to the tuberculum bacillus.
There is a strong female predominance of the disease Individual lesions typically heal slowly over the course of several months, but may persist for years without appropriate treatment.
Create a personal account to register for email alerts with bwzin to free full-text articles. Feiwel, M, Munro, DD.
Mycobacterium-related cutaneous conditions Infection-related cutaneous condition stubs. Lupus profundus also known as lupus panniculitis, differentiated clinically by its more characteristic location on the face and tendency to cause lipodystrophy due to complete destruction of the involved fat cells. No pathognomonic histologic feature of erythema induratum exists, and histologic findings may vary with the age of the lesion Figure 2.
Laboratory tests Additional laboratory tests including a complete bazzin count with differential, chemistry panel, erythrocyte sedimentation rate, and liver function tests are typically normal in erythema induratum. Encourage patients to persist with treatment. Ulcerated nodules exhibit overlying crust with a rolled erythematous, blue-tinged border.
Erythema induratum classically presents during early adolescence and peri-menopause as subcutaneous poorly defined erythematous plaques and tender violaceous nodules. As such, once a diagnosis of a tuberculid is made, a thorough investigation to evaluate for subclinical or active TB infection should be pursued.
Erythema induratum – Wikipedia
We describe a patient with El in whom the diagnosis of tuberculosis could be established by the detection of mycobacterial DNA in a lesional biopsy specimen using the polymerase chain reaction PCR. Erythema induratum is characterized by painful, erythematous, sometimes ulcerating nodules on the lower legs that, histopathologically, show a lobular panniculitis.
When weather is cold, ankle indurtaum cold, blue and often tender. Histology will demonstrate a lobular panniculitis with ghost adipoyctes adipocytes with fine granular basophilic material and no nuclei and necrosis of adipocytes.
Erythema induratum of bazin.
Retrieved from ” https: Patients with active disease require co-management with appropriate specialists. Purchase access Subscribe to the journal.
In these situations, a high index of clinical suspicion is required. Men and even young children may present baxin the disease, and lesions may appear in unusual locations including the feet, buttocks, thighs, arms and rarely the face and ears. You can help Wikipedia by expanding it.
If an active focus of TB is uncovered, appropriate imaging studies should be performed at regular intervals to monitor regression of disease. This page was last edited on erktema Julyat Erutema, all states require a communicable disease report to be filed with the local county public health department, generally within 24 hours of identification. Additional laboratory tests including a complete blood count with differential, chemistry panel, erythrocyte sedimentation rate, and liver function tests are typically normal in erythema induratum.
Erythema induratum of bazin.
Caseation necrosis is a late finding evident in approximately one half of cases. Purchase access Subscribe now.
Subcutaneous erittema with overlying poorly defined violaceous erythema on the posterior leg The plaques are generally erythematous and indurated, with an overlying scaly surface, and may or may not be tender to deep palpation.
Other Early morning sputum, urine and gastric aspirates may be helpful to rule out an underlying active infection, but are generally negative. Lobular without vasculitis Cold Cytophagic histiocytic Factitial Gouty Pancreatic Traumatic needle-shaped clefts Subcutaneous fat necrosis of the newborn Sclerema neonatorum Post-steroid panniculitis Lipodermatosclerosis Weber—Christian disease Lupus erythematosus hazin Sclerosing lipogranuloma with vasculitis: Create a free personal account to make a comment, download free article PDFs, sign up for alerts and more.
Sign in to customize your interests Sign in to your personal account. While there are no risk factors other than previous inxuratum to TB per se, cold weather, venous stasis with poor peripheral blood flow and obesity appear to precipitate the development of lesions. Fresh crops of nodules appear in periphery of ulcer and ultimately break down.