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When Maria Vrind, a former gymnast from Volendam in the Netherlands, found that the only way she could put her socks on in the morning was to bowwn on her back with her feet in the air, she had to accept that things had reached a crisis point.
Vrind was in her late 40s and working two jobs, athletics coach and a carer for disabled people, but her condition now began taking over her tehnlka. Her knees, ankles, wrists, elbows and shoulder joints were hot and inflamed. It was rheumatoid arthritis, a common but incurable autoimmune disorder in which the body attacks its own cells, in this case the lining of the joints, producing chronic inflammation and bone deformity.
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Waiting rooms outside rheumatoid arthritis clinics used to be tehniia of people in wheelchairs. Not everyone feels better, however: Like many patients, Vrind was given several different medications, including painkillers, a cancer drug called methotrexate to dampen her entire immune system, and biopharmaceuticals to block the production of specific inflammatory proteins.
The drugs did their job well enough — at least, they did until one day inwhen they stopped working. Luckily, she would not have to.
As she was resigning herself to a life of disability and monthly chemotherapy, a new treatment was being developed that would profoundly challenge our understanding of how the brain and body interact to control the immune system. It would open up a whole new tehhnika to treating rheumatoid arthritis and other autoimmune diseases, using the nervous system to modify inflammation.
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It would even lead to research into how we might use our minds to stave off disease. And, like many good ideas, it came from an unexpected source.
Ipak, ne mora da bude tako.